To find giant black holes, start with Jupiter

Illustration of black hole, warped spacetime (stock image).

The revolution in our understanding of the night sky and our place in the universe began when we transitioned from using the naked eye to a telescope in 1609. Four centuries later, scientists are experiencing a similar transition in their knowledge of black holes by searching for gravitational waves.

In the search for previously undetected black holes that are billions of times more massive than the sun, Stephen Taylor, assistant professor of physics and astronomy and former astronomer at NASA's Jet Propulsion Laboratory (JPL) together with the North American Nanohertz Observatory for Gravitational Waves (NANOGrav) collaboration has moved the field of research forward by finding the precise location -- the center of gravity of our solar system -- with which to measure the gravitational waves that signal the existence of these black holes.

The potential presented by this advancement, co-authored by Taylor, was published in the journal the Astrophysical Journal in April 2020.

Black holes are regions of pure gravity formed from extremely warped spacetime. Finding the most titanic black holes in the Universe that lurk at the heart of galaxies will help us understand how such galaxies (including our own) have grown and evolved over the billions of years since their formation. These black holes are also unrivaled laboratories for testing fundamental assumptions about physics.

Gravitational waves are ripples in spacetime predicted by Einstein's general theory of relativity. When black holes orbit each other in pairs, they radiate gravitational waves that deform spacetime, stretching and squeezing space. Gravitational waves were first detected by the Laser Interferometer Gravitational-Wave Observatory (LIGO) in 2015, opening new vistas on the most extreme objects in the universe. Whereas LIGO observes relatively short gravitational waves by looking for changes in the shape of a 4-km long detector, NANOGrav, a National Science Foundation (NSF) Physics Frontiers Center, looks for changes in the shape of our entire galaxy.

Taylor and his team are searching for changes to the arrival rate of regular flashes of radio waves from pulsars. These pulsars are rapidly spinning neutron stars, some going as fast as a kitchen blender. They also send out beams of radio waves, appearing like interstellar lighthouses when these beams sweep over Earth. Over 15 years of data have shown that these pulsars are extremely reliable in their pulse arrival rates, acting as outstanding galactic clocks. Any timing deviations that are correlated across lots of these pulsars could signal the influence of gravitational waves warping our galaxy.

"Using the pulsars we observe across the Milky Way galaxy, we are trying to be like a spider sitting in stillness in the middle of her web," explains Taylor. "How well we understand the solar system barycenter is critical as we attempt to sense even the smallest tingle to the web." The solar system barycenter, its center of gravity, is the location where the masses of all planets, moons, and asteroids balance out.

Where is the center of our web, the location of absolute stillness in our solar system? Not in the center of the sun as many might assume, rather it is closer to the surface of the star. This is due to Jupiter's mass and our imperfect knowledge of its orbit. It takes 12 years for Jupiter to orbit the sun, just shy of the 15 years that NANOGrav has been collecting data. JPL's Galileo probe (named for the famed scientist that used a telescope to observe the moons of Jupiter) studied Jupiter between 1995 and 2003, but experienced technical maladies that impacted the quality of the measurements taken during the mission.

Identifying the center of the solar system's gravity has long been calculated with data from Doppler tracking to get an estimate of the location and trajectories of bodies orbiting the sun. "The catch is that errors in the masses and orbits will translate to pulsar-timing artifacts that may well look like gravitational waves," explains JPL astronomer and co-author Joe Simon.

Taylor and his collaborators were finding that working with existing solar system models to analyze NANOGrav data gave inconsistent results. "We weren't detecting anything significant in our gravitational wave searches between solar system models, but we were getting large systematic differences in our calculations," notes JPL astronomer and the paper's lead author Michele Vallisneri. "Typically, more data delivers a more precise result, but there was always an offset in our calculations."

The group decided to search for the center of gravity of the solar system at the same time as sleuthing for gravitational waves. The researchers got more robust answers to finding gravitational waves and were able to more accurately localize the center of the solar system's gravity to within 100 meters. To understand that scale, if the sun were the size of a football field, 100 meters would be the diameter of a strand of hair. "Our precise observation of pulsars scattered across the galaxy has localized ourselves in the cosmos better than we ever could before," said Taylor. "By finding gravitational waves this way, in addition to other experiments, we gain a more holistic overview of all different kinds of black holes in the Universe."

As NANOGrav continues to collect ever more abundant and precise pulsar timing data, astronomers are confident that massive black holes will show up soon and unequivocally in the data.

Taylor was partially supported by an appointment to the NASA Postdoctoral Program at JPL. The NANOGrav project receives support from the NSF Physics Frontier Center award #1430284 and this work was supported in part by NSF Grant PHYS-1066293 and by the hospitality of the Aspen Center for Physics. Data for this project were collected using the facilities of the Green Bank Observatory and the Arecibo Observatory.

---

Story Source:

Materials provided by Vanderbilt University. Original written by Marissa Shapiro. Note: Content may be edited for style and length.

---

Journal Reference:

1. M. Vallisneri, S. R. Taylor, J. Simon, W. M. Folkner, R. S. Park, C. Cutler, J. A. Ellis, T. J. W. Lazio, S. J. Vigeland, K. Aggarwal, Z. Arzoumanian, P. T. Baker, A. Brazier, P. R. Brook, S. Burke-Spolaor, S. Chatterjee, J. M. Cordes, N. J. Cornish, F. Crawford, H. T. Cromartie, K. Crowter, M. DeCesar, P. B. Demorest, T. Dolch, R. D. Ferdman, E. C. Ferrara, E. Fonseca, N. Garver-Daniels, P. Gentile, D. Good, J. S. Hazboun, A. M. Holgado, E. A. Huerta, K. Islo, R. Jennings, G. Jones, M. L. Jones, D. L. Kaplan, L. Z. Kelley, J. S. Key, M. T. Lam, L. Levin, D. R. Lorimer, J. Luo, R. S. Lynch, D. R. Madison, M. A. McLaughlin, S. T. McWilliams, C. M. F. Mingarelli, C. Ng, D. J. Nice, T. T. Pennucci, N. S. Pol, S. M. Ransom, P. S. Ray, X. Siemens, R. Spiewak, I. H. Stairs, D. R. Stinebring, K. Stovall, J. K. Swiggum, R. van Haasteren, C. A. Witt, W. W. Zhu. Modeling the Uncertainties of Solar System Ephemerides for Robust Gravitational-wave Searches with Pulsar-timing Arrays. The Astrophysical Journal, 2020; 893 (2): 112 DOI: 10.3847/1538-4357/ab7b67

The mysterious, legendary giant squid's genome is revealed.

How did the monstrous giant squid -- reaching school-bus size, with eyes as big as dinner plates and tentacles that can snatch prey 10 yards away -- get so scarily big?

Today, important clues about the anatomy and evolution of the mysterious giant squid (Architeuthis dux) are revealed through publication of its full genome sequence by a University of Copenhagen-led team that includes scientist Caroline Albertin of the Marine Biological Laboratory (MBL), Woods Hole.

Giant squid are rarely sighted and have never been caught and kept alive, meaning their biology (even how they reproduce) is still largely a mystery. The genome sequence can provide important insight.

"In terms of their genes, we found the giant squid look a lot like other animals. This means we can study these truly bizarre animals to learn more about ourselves," says Albertin, who in 2015 led the team that sequenced the first genome of a cephalopod (the group that includes squid, octopus, cuttlefish, and nautilus).

Led by Rute da Fonseca at University of Copenhagen, the team discovered that the giant squid genome is big: with an estimated 2.7 billion DNA base pairs, it's about 90 percent the size of the human genome.

Albertin analyzed several ancient, well-known gene families in the giant squid, drawing comparisons with the four other cephalopod species that have been sequenced and with the human genome.

She found that important developmental genes in almost all animals (Hox and Wnt) were present in single copies only in the giant squid genome. That means this gigantic, invertebrate creature -- long a source of sea-monster lore -- did NOT get so big through whole-genome duplication, a strategy that evolution took long ago to increase the size of vertebrates.

So, knowing how this squid species got so giant awaits further probing of its genome.

"A genome is a first step for answering a lot of questions about the biology of these very weird animals," Albertin said, such as how they acquired the largest brain among the invertebrates, their sophisticated behaviors and agility, and their incredible skill at instantaneous camouflage.

"While cephalopods have many complex and elaborate features, they are thought to have evolved independently of the vertebrates. By comparing their genomes we can ask, 'Are cephalopods and vertebrates built the same way or are they built differently?'" Albertin says.

Albertin also identified more than 100 genes in the protocadherin family -- typically not found in abundance in invertebrates -- in the giant squid genome.

"Protocadherins are thought to be important in wiring up a complicated brain correctly," she says. "They were thought they were a vertebrate innovation, so we were really surprised when we found more than 100 of them in the octopus genome (in 2015). That seemed like a smoking gun to how you make a complicated brain. And we have found a similar expansion of protocadherins in the giant squid, as well."

Lastly, she analyzed a gene family that (so far) is unique to cephalopods, called reflectins. "Reflectins encode a protein that is involved in making iridescence. Color is an important part of camouflage, so we are trying to understand what this gene family is doing and how it works," Albertin says.

"Having this giant squid genome is an important node in helping us understand what makes a cephalopod a cephalopod. And it also can help us understand how new and novel genes arise in evolution and development."

---

Story Source:

Materials provided by Marine Biological Laboratory. Original written by Diana Kenney. Note: Content may be edited for style and length.

Why are giant pandas born so tiny?

Panda babies

Born pink, blind, and helpless, giant pandas typically weigh about 100 grams at birth -- the equivalent of a stick of butter. Their mothers are 900 times more massive than that.

This unusual size difference has left researchers puzzled for years. With a few exceptions among animals such as echidnas and kangaroos, no other mammal newborns are so tiny relative to their mothers. No one knows why, but a Duke University study of bones across 10 species of bears and other animals finds that some of the current theories don't hold up.

Duke biology professor Kathleen Smith and her former student Peishu Li published their findings this month in the Journal of Anatomy.

Baby panda skeletons are hard to come by, but the researchers were able to study the preserved remains of baby pandas born at the Smithsonian's National Zoo in Washington, D.C.

The National Zoo's first panda couple, Ling-Ling and Hsing-Hsing, had five full-term cubs in the 1980s, but none of them survived long after birth.

The researchers took micro-CT scans of two of those cubs, along with newborn grizzlies, sloth bears, polar bears, dogs, a fox, and other closely related animals from the Smithsonian National Museum of Natural History and the North Carolina State College of Veterinary Medicine.

They used the scans to create 3-D digital models of each baby's bony interior at birth.

As a baby animal grows and develops inside the womb, its bones and teeth do, too. The researchers examined the degree of ossification, or how much the skeleton has formed by the time of birth. They looked at whether the teeth had started to calcify or erupt, and the degree of fusion between the bony plates that make up the skull.

The panda may be an extreme example, but all bears have disproportionately small babies, Li said. A newborn polar bear's birthweight as a fraction of mom's is less than 1:400, or less than one-half of one percent of her body mass. For the vast majority of baby mammals, including humans, the average is closer to 1:26.

One decades-old idea links low birthweights in bears to the fact that, for some species, pregnancy overlaps with winter hibernation. Pregnant females don't eat or drink during this time, relying mostly on their fat reserves to survive, but also breaking down muscle to supply protein to the fetus.

The thinking is that, energetically, females can only afford to nourish their babies this way for so long before this tissue breakdown threatens their health. By cutting pregnancy short and giving birth to small, immature babies, bears would shift more of their growth to outside the womb, where babies can live off their mother's fat-rich milk instead of depleting her muscles.

Proponents of the theory concede that not all bears -- including pandas -- hibernate during the winter. But the idea is that small birthweight is 'locked in' to the bear family tree, preventing non-hibernating relatives from evolving bigger babies too.

"It's certainly an appealing hypothesis," Smith said.

But the Duke team's research shows this scenario is unlikely. The researchers didn't find any significant differences in bone growth between hibernating bears and their counterparts that stay active year-round and don't fast during pregnancy.

In fact, despite being small, the researchers found that most bear skeletons are just as mature at birth as their close animal cousins.

The panda bear is the one exception to this rule, results show. Even in a full-term baby panda, the bones look a lot like those of a beagle puppy delivered several weeks premature.

"That would be like a 28-week human fetus" at the beginning of the third trimester, Smith said.

Other factors might have pushed panda babies toward smaller sizes over time -- some researchers blame their bamboo-only diet -- but data are scarce, Li said. The researchers say the panda bear's embryonic appearance likely has to do with a quirk of panda pregnancy.

All bears experience what's called "delayed implantation." After the egg is fertilized, the future fetus enters a state of suspended animation, floating in the womb for several months before implanting in the uterine wall to resume its development and get ready for birth.

But while other bears gestate for two months after implantation, giant pandas are done in a month.

"They're basically undercooked," said Li, now a Ph.D. student at the University of Chicago.

The researchers say they only looked at skeletons in this study, and it could be that other organs like the brain tell a different story. But the new study suggests that baby pandas follow the same trajectory as other mammal relatives -- their bones mature in the same sequence and at similar rates -- but on a truncated timetable.

"Development is just cut short," Smith said.

Scientists are still searching for a complete explanation of why the panda's peculiar size differential evolved over geological time, and how.

"We really need more information about their ecology and reproduction in the wild," Smith said, and we may not have much time given their risk of extinction. But this study brings them one step closer to an answer.

This research was supported by a Shared Material Instrumentation Facility Undergraduate User Program grant, the Duke Department of Biology, and the Undergraduate Research Office at Duke.

Story Source:

Materials provided by Duke University. Original written by Robin A. Smith. Note: Content may be edited for style and length.

Extinct giant ape directly linked to the living orangutan

Modern-day orangutan

By using ancient protein sequencing, researchers have retrieved genetic information from a 1.9 million year old extinct, giant primate that used to live in a subtropical area in southern China. The genetic information allows the researchers to uncover the evolutionary position of Gigantopithecus blacki, a three-meter tall and may be up to 600 kg heavy primate, revealing the orangutan as its closest, living relative.

It is the first time that genetic material this old has been retrieved from a warm, humid environment. The study is published in the scientific journal Nature, and the results are groundbreaking within the field of evolutionary biology, according to Frido Welker, Postdoc at the Globe Institute at the Faculty of Health and Medical Sciences and first author of the study.

'Primates are relatively close to humans, evolutionary speaking. With this study, we show that we can use protein sequencing to retrieve ancient genetic information from primates living in subtropical areas even when the fossil is two million years old. Until now, it has only been possible to retrieve genetic information from up to 10,000-year-old fossils in warm, humid areas. This is interesting, because ancient remains of the supposed ancestors of our species, Homo sapiens, are also mainly found in subtropical areas, particularly for the early part of human evolution. This means that we can potentially retrieve similar information on the evolutionary line leading to humans', says Frido Welker.

Today, scientists know that the human and the chimpanzee lineages split around seven or eight million years ago. With the previous methodologies though, they could only retrieve human genetic information not older than 400,000 years. The new results show the possibility to extend the genetic reconstruction of the evolutionary relationships between our species and extinct ones further back in time, at least up to two million years -- covering a much larger portion of the entire human evolution.

Analyzing ancient dental enamel proteins using mass spectrometry-based proteomics

In a recent study, also published on Nature, Enrico Cappellini, Associate Professor at the Globe Institute and senior author on this study, initially demonstrated, together with an international team of colleagues, the massive potential of ancient protein sequencing.

'By sequencing proteins retrieved from dental enamel about two million years old, we showed it is possible to confidently reconstruct the evolutionary relationships of animal species that went extinct too far away in time for their DNA to survive till now. In this study, we can even conclude that the lineages of orangutan and Gigantopithecus split up about 12 million years ago', says Enrico Cappellini.

Sequencing protein remains two million years old was made possible by stretching to its limits the technology at the base of proteomic discovery: mass spectrometry. State of the art mass spectrometers and the top palaeoproteomics expertise needed to get the best out of such sophisticated instrumentation are key resources deriving from the decade-long strategic collaboration with Jesper Velgaard Olsen, Professor at Novo Nordisk Foundation Center for Protein Research and co-author on this study.

The mystery of Gigantopithecus

The fossil evidence attributed to Gigantopithecus was initially discovered in southern China in 1935, and it is currently limited to just a few lower jaws and lots of teeth. No complete skull and no other bone from the rest of the skeleton has been found so far. As a result, there has been a lot of speculation about the physical appearance of this mysterious animal.

'Previous attempts to understand which could be the living organism most similar to Gigantopithecus could only be based on the comparison of the shape of the fossils with skeletal reference material from living great apes. Ancient DNA analysis was not an option, because Gigantopithecus went extinct approximately 300,000 years ago, and in the geographic area Gigantopithecus occupied no DNA older than approximately 10,000 years has been retrieved so far. Accordingly, we decided to sequence dental enamel proteins to reconstruct its evolutionary relation with living great apes, and we found that orangutan is Gigantopithecus' closest living relative', says Enrico Cappellini.

The study of human evolution by palaeoproteomics will continue in the next years through the recently established "Palaeoproteomics to Unleash Studies on Human History (PUSHH)" Marie Sk?odowska Curie European Training Network (ETN) Programme.

The research is funded mainly by VILLUM FONDEN, the Novo Nordisk Foundation, and the Marie Sklowowska-Curie Actions Individual Fellowship and International Training Network programmes.

---

Story Source:

Materials provided by University of Copenhagen The Faculty of Health and Medical Sciences. Note: Content may be edited for style and length.

---

Related Multimedia:

• Images of fossil mandible and artist's rendering of Gigantopithecus blacki

Extinct giant ape directly linked to the living orangutan

Modern day orangutan

By using ancient protein sequencing, researchers have retrieved genetic information from a 1.9 million year old extinct, giant primate that used to live in a subtropical area in southern China. The genetic information allows the researchers to uncover the evolutionary position of Gigantopithecus blacki, a three-meter tall and may be up to 600 kg heavy primate, revealing the orangutan as its closest, living relative.

It is the first time that genetic material this old has been retrieved from a warm, humid environment. The study is published in the scientific journal Nature, and the results are groundbreaking within the field of evolutionary biology, according to Frido Welker, Postdoc at the Globe Institute at the Faculty of Health and Medical Sciences and first author of the study.

'Primates are relatively close to humans, evolutionary speaking. With this study, we show that we can use protein sequencing to retrieve ancient genetic information from primates living in subtropical areas even when the fossil is two million years old. Until now, it has only been possible to retrieve genetic information from up to 10,000-year-old fossils in warm, humid areas. This is interesting, because ancient remains of the supposed ancestors of our species, Homo sapiens, are also mainly found in subtropical areas, particularly for the early part of human evolution. This means that we can potentially retrieve similar information on the evolutionary line leading to humans', says Frido Welker.

Today, scientists know that the human and the chimpanzee lineages split around seven or eight million years ago. With the previous methodologies though, they could only retrieve human genetic information not older than 400,000 years. The new results show the possibility to extend the genetic reconstruction of the evolutionary relationships between our species and extinct ones further back in time, at least up to two million years -- covering a much larger portion of the entire human evolution.

Analyzing ancient dental enamel proteins using mass spectrometry-based proteomics

In a recent study, also published on Nature, Enrico Cappellini, Associate Professor at the Globe Institute and senior author on this study, initially demonstrated, together with an international team of colleagues, the massive potential of ancient protein sequencing.

'By sequencing proteins retrieved from dental enamel about two million years old, we showed it is possible to confidently reconstruct the evolutionary relationships of animal species that went extinct too far away in time for their DNA to survive till now. In this study, we can even conclude that the lineages of orangutan and Gigantopithecus split up about 12 million years ago', says Enrico Cappellini.

Sequencing protein remains two million years old was made possible by stretching to its limits the technology at the base of proteomic discovery: mass spectrometry. State of the art mass spectrometers and the top palaeoproteomics expertise needed to get the best out of such sophisticated instrumentation are key resources deriving from the decade-long strategic collaboration with Jesper Velgaard Olsen, Professor at Novo Nordisk Foundation Center for Protein Research and co-author on this study.

The mystery of Gigantopithecus

The fossil evidence attributed to Gigantopithecus was initially discovered in southern China in 1935, and it is currently limited to just a few lower jaws and lots of teeth. No complete skull and no other bone from the rest of the skeleton has been found so far. As a result, there has been a lot of speculation about the physical appearance of this mysterious animal.

'Previous attempts to understand which could be the living organism most similar to Gigantopithecus could only be based on the comparison of the shape of the fossils with skeletal reference material from living great apes. Ancient DNA analysis was not an option, because Gigantopithecus went extinct approximately 300,000 years ago, and in the geographic area Gigantopithecus occupied no DNA older than approximately 10,000 years has been retrieved so far. Accordingly, we decided to sequence dental enamel proteins to reconstruct its evolutionary relation with living great apes, and we found that orangutan is Gigantopithecus' closest living relative', says Enrico Cappellini.

The study of human evolution by palaeoproteomics will continue in the next years through the recently established "Palaeoproteomics to Unleash Studies on Human History (PUSHH)" Marie Sk?odowska Curie European Training Network (ETN) Programme.

The research is funded mainly by VILLUM FONDEN, the Novo Nordisk Foundation, and the Marie Sklowowska-Curie Actions Individual Fellowship and International Training Network programmes.

---

Story Source:

Materials provided by University of Copenhagen The Faculty of Health and Medical Sciences. Note: Content may be edited for style and length.