A 27-year-old British soldier on Putin's hitlist calls it a 'badge of honour.'

Fraser Good, a British citizen, delivered a defiant message upon learning that his name had been added to a Russian-operated wanted list. A British veteran has reaffirmed his pride in supporting Ukraine after finding his name and photo on a Russian wanted list. Fraser Good shared with Metro that being listed in the flawed database is a "badge of honour," symbolizing his service, which has seen him involved in some of the war's fiercest battles. The list also features British nationals who have died during humanitarian missions or in combat against Vladimir Putin's forces, with some names marked as "destroyed." Fraser Good served on some of the war's most intense frontlines, including the battle for Kyiv, the liberation of Irpin, and operations near Kharkiv. He suffered severe injuries from a tank round while he and a small group of comrades defended their position against a massive Russian assault in Donetsk. Reflecting on the list, Fraser remarked: “It would be nice if they could at least get one date right—the details are completely wrong. “I definitely see being named on the list as a badge of honour. “If anything, I want the enemy to know who I am, because I am proud to stand with Ukraine.” The 27-year-old combat veteran from Northamptonshire, who served seven years in the British Army, has been living in Ukraine since March 2022 and is currently out of contract with the military. He has previously been the focus of Russian propaganda, with false claims circulated twice alleging that he had been killed in the war zone.

Fraser Good has fought in intense frontline battles as part of Ukraine's struggle for freedom. In a Facebook post, he wrote: "My comrades and I will keep fighting until Ukraine is free. It's as simple as that. Your propaganda and politics have been tiresome for as long as I can remember. Swipe for a surprise... Yep, that's me. Still very much alive and smiling, with more than one eye captured this morning. Honestly, you all bore me." "I take great satisfaction in proving each and every one of you wrong, every single time." The list, reportedly created by pro-Russian volunteers, contains personal information like phone numbers and email addresses, indicating the data may have been acquired through questionable means, possibly in collaboration with Kremlin sources. The entries also feature exaggerated criminal charges, likely aimed at justifying severe punishments or enabling exchanges for high-value prisoners held by Ukraine and its allies if these individuals are captured. Metro interviewed three British nationals and one American, none of whom were aware they were listed. The website is registered with a Russian URL and an IP address in Rostov-on-Don, a heavily militarized city in southern Russia.

After Russia's full-scale invasion began, Fraser Good left his life in the East Midlands behind to start a new chapter in Ukraine (Picture: Fraser Good, Facebook). A Scotsman named in the database referred to Putin as "an evil little bastard" after *Metro* informed him of his inclusion. Mike Marley, a former British Army soldier with 20 years of service who later transitioned to civilian life, shared with *Metro* that he had considered joining the International Legion for the Defense of Ukraine but decided against it. In November 2023, Russian media reported that hackers from a group called Joker DPR had released the names and personal details of over 500 applicants to the Legion. *Metro* has contacted the formation for comment. "They've clearly gained access to documents from people who showed interest in going to Ukraine," said Mr. Marley. "I was planning to go, but at my age and with my injuries, I decided against it. They must have gotten hold of documents from the International Legion, which probably included my name. "It's a bit concerning that they've accessed my information. "However, in practical terms, it likely just means I can't go to Russia now—which I wouldn't want to do anyway."

Drivers stranded on 401 as blizzard pounds parts of southwestern Ontario

Drivers travelling on Highway 401 in southwestern Ontario found themselves stranded for hours as a major snow storm hit the region Thursday causing collisions and closures. Motorists who spoke to CBC News from their vehicles said they called local and provincial police many times but received no answers, adding they weren't prepared to be stuck for such a long time. "We are now many hours deep into this, sitting still on the road and nobody has come to check on us," said Craig Sears in an interview from the 401 where he sat with his wife and son enroute to Sarnia. "I'm a diabetic and we have our son with us who has Aspergers, so he's feeling uncomfortable. It's super anxious for him because we've literally been sitting here for five hours, not getting any responses from police," Sears said. London and surrounding area faced multiple road closures, crashes and difficult driving conditions throughout the afternoon and night as heavy snowfall blanketed the region. Environment Canada expected an additional 30 cm to fall by morning, with the squalls continuing. A multi-vehicle crash closed the westbound lanes of Highway 401 near Ingersoll in the afternoon, with police keeping them closed until almost 6 p.m. The OPP said one person was taken to hospital in critical condition. "I can tell everybody who's stranded right now, their patience is running thin, I totally understand that," OPP Sgt. Sanchuk said urging drivers to stay in their vehicles and to be patient. "We have officers turning traffic around on our highway right now and we have officers strategically placed to get people off the highway in a safe manner. But please bare with us, we're working as diligently as possible to get the highway cleared." Traffic 'at a standstill' drivers say Jackie Lemmink was stuck on the 401, east of London, for more than six hours while officers dealt with the crash. She witnessed multiple additional collisions in front of her before traffic came to a stop. "It doesn't look like anything's moving," she told CBC London's Afternoon Drive from her vehicle. "There are trucks upon trucks, and there's so much traffic that's at a standstill. People are starting to come out of their cars to find out what's going on because we don't have any idea."

A series of collisions forced the closure of westbound Highway 401 near Ingersoll on Thursday afternoon. Many drivers were left sitting on their vehicles while police dealt with the collisions. (Submitted by OPP) Lemmink, who was on her way to Michigan, said she opted not to take county roads because she assumed the 401 would be safer due to constantly moving traffic. "I always thought the 401 is safer because they'll put down salt and they've prepared for this. The snow is quite high and it's quite icy everywhere. I'm not prepared to be stuck here." Sears said he was forced to turn off his car to save fuel at the 5 hour mark of waiting. He said traffic had begun to crawly slowly around 8 p.m. but that the conditions were still poor. "It's insane because I've called [police] multiple times. Shouldn't they check on people? Nobody should ever be trapped in their vehicle on a highway for this long, there's no excuse for it," he said. Police continued to warn people to stay off the roads, and to only travel is absolutely necessary.

Mysterious holes found on ocean floor have scientists ‘stumped’

These linear, peculiar-looking openings in the sand could be human made. But a more plausible explanation might be that they’re tracks left behind by an undiscovered species lurking in the deep sea. The depths of the Earth's oceans contain many secrets that often take researchers years of investigation to solve. A new mystery in the Atlantic Ocean is almost literally taking them down the rabbit hole. On July 23, along the seafloor off the coast of Portugal beneath the island chain of the Azores, scientists working with the National Oceanic and Atmospheric Administration (NOAA) found a dozen sets of small holes in the sand at a depth of nearly 2 miles, with no clues of how they got there. Two weeks later and 300 miles away, they found even more mysterious holes, exactly the same as the first.

A close look at the sets of holes along the floors of the Atlantic Ocean. The origins of the holes are unclear. (NOAA Ocean Exploration) From May to September 2022, NOAA is carrying out an expedition called Voyage to the Ridge 2022 in this relatively unexplored region of the Atlantic. NOAA scientists set off from Newport, Rhode Island, to Newfoundland, Canada, on the first leg of the trip and then left Norfolk, Virginia, for the Azores. They will finish up by traversing the Atlantic in the other direction, to Puerto Rico and the Caribbean. Their research vessel, called the Okeanos Explorer, is investigating the coral and sponge colonies on volcanic ridges. Finding the holes was more of a happy accident. This isn't the first time scientists encountered these strange-looking patterns. NOAA spokesperson Emily Crum told The New York Times that in 2004, right in the vicinity of this initial discovery, researchers recorded the first sighting of the holes. “The origin of the holes has scientists stumped,” NOAA's Ocean Exploration project tweeted. “The holes look human made, but the little piles of sediment around them suggest they were excavated by … something.” “There is something important going on there and we don’t know what it is,” NOAA deep-sea biologist Michael Vecchione told the Times. “This highlights the fact that there are still mysteries out there.” Hypotheses regarding the origins of the holes range from human-made causes to the tracks of an undiscovered species of animal or a gas vent blowing bubbles up through the sand. Vecchione co-authored a paper in 2022 discussing the gaps in current knowledge of the holes and what could be causing them. According to the paper, the holes appear to have been either excavated from the top or pierced up from underneath, meaning whatever created them could have been digging the holes or burrowed under the sediment and potentially used the holes as a breathing apparatus -- like a snorkel. There's no definitive evidence to say for sure, though, and it will take more time and investigations to find the truth.

NOAA scientists use this underwater drone, called Deep Discoverer, to examine features of the seafloor up to 19,000 feet below the ocean's surface. (NOAA Ocean Exploration) Vecchione, who was present for this latest run-in with the mysterious holes, said he was happy to see them again after nearly two decades but also expressed disappointment that there are still no answers. The Okeanos Explorer is currently docked in the Azores until Aug. 6, when the vessel will set out for its third Voyage to the Ridge expedition.

Receptor makes mice strong and slim

Mouse on exercise wheel (stock image).

Increasing abdominal girth and shrinking muscles are two common side effects of aging. Researchers at the University of Bonn have discovered a receptor in mice that regulates both effects. Experiments with human cell cultures suggest that the corresponding signaling pathways might also exist in humans. The study, which also involved researchers from Spain, Finland, Belgium, Denmark and the USA, has now been published in the journal Cell Metabolism.

On their surface, cells carry numerous different "antennas," called receptors, which can receive specific signal molecules. These then trigger a specific reaction in the cell. One of these antennas is the A2B receptor. The surfaces of some cells are virtually teeming with it, for example in the so-called brown adipose tissue. Brown adipose tissue, unlike its white-colored counterpart, is not used to store fat. Instead, it burns fat and thereby generates heat.

"In our publication we took a closer look at the A2B receptors in brown adipose tissue," explains Prof. Dr. Alexander Pfeifer from the Institute of Pharmacology and Toxicology at the University Hospital Bonn. "In the course of this we discovered an interesting association: The more A2B a mouse produces, the more heat it generates." Which means the A2B antennas somehow seem to increase the activity of the brown fat cells. But a second observation was even more exciting: Despite their increased fat burning, the animals weigh hardly less than mice with fewer receptors. "They are slimmer, but at the same time have more muscles," explains Pfeifer.

Muscles like a young mouse

In fact, the researchers were able to show that the muscle cells of mice also carry the A2B receptor. When this is stimulated by a small molecule agonist, muscle growth in the rodents is increased. "The receptor regulates both fat burning and muscle development," emphasizes Pfeifer's colleague Dr. Thorsten Gnad, the lead author of the study.

As they age, mice increasingly lose muscle mass -- similar to humans. And just like us, they also tend to gain a lot of fat around the hips over the years. However, if they receive the agonist that activates the A2B receptor, these aging effects are inhibited: Their oxygen consumption (an indicator of energy dissipation) increases by almost half; moreover, after four weeks of treatment they have as much muscle mass as a young animal. "A2B activation can therefore reverse both aging effects to a certain extent," explains Gnad.

In order to see whether the results were also meaningful for humans, the researchers examined human cell cultures and tissue samples. They found that in people with a large number of A2B receptors, the brown adipose tissue works at a higher rate. At the same time, their muscle cells consume more energy, which may indicate that they are also more active and may be more likely to be regenerated.

"Obesity is a growing problem worldwide," emphasizes Prof. Pfeifer. "Every extra pound not only increases the risk of developing diabetes, but also the risk of high blood pressure, vascular damage and therefore heart attacks and strokes. These problems are further exacerbated by muscles that shrink over the years, as they further reduce the body's energy requirements both at rest and in motion." In addition, poor muscle strength has an immense impact on the everyday life of older people, as they are increasingly restricted in their mobility.

The pharmacologists explain that the prospect of having a receptor on hand that might be able to slow down both of these age-related phenomena is therefore highly exciting. However, further research would first have to show to what extent the human mechanisms actually resemble those in mice. Additionally, there is currently no activator of A2B approved for use in humans. This means that little is known about any side effects of such a treatment. "We found no signs of adverse reactions in mice," says Pfeifer. "However, the meaningfulness of the results is, of course, also limited on this matter."

Gnad emphasizes that the success of the study is also the result of good cooperation with numerous international partners: "Nowadays, it is almost impossible to work on complex issues comprehensively without such cooperation."

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Materials provided by University of Bonn. Note: Content may be edited for style and length.

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Journal Reference:

1. Thorsten Gnad, Gemma Navarro, Minna Lahesmaa, Laia Reverte-Salisa, Francesca Copperi, Arnau Cordomi, Jennifer Naumann, Aileen Hochhäuser, Saskia Haufs-Brusberg, Daniela Wenzel, Frank Suhr, Naja Zenius Jespersen, Camilla Scheele, Volodymyr Tsvilovskyy, Christian Brinkmann, Joern Rittweger, Christian Dani, Mathias Kranz, Winnie Deuther-Conrad, Holger K. Eltzschig, Tarja Niemi, Markku Taittonen, Peter Brust, Pirjo Nuutila, Leonardo Pardo, Bernd K. Fleischmann, Matthias Blüher, Rafael Franco, Wilhelm Bloch, Kirsi A. Virtanen, Alexander Pfeifer. Adenosine/A2B Receptor Signaling Ameliorates the Effects of Aging and Counteracts Obesity. Cell Metabolism, 2020; DOI: 10.1016/j.cmet.2020.06.006

Synchrotron X-ray sheds light on some of the world's oldest dinosaur eggs

An international team of scientists led by the University of the Witwatersrand in South Africa, has been able to reconstruct, in the smallest details, the skulls of some of the world's oldest known dinosaur embryos in 3D, using powerful and non-destructive synchrotron techniques at the ESRF, the European Synchrotron in France. They found that the skulls develop in the same order as those of today's crocodiles, chickens, turtles and lizards. The findings are published today in Scientific Reports.

University of the Witwatersrand scientists publish 3D reconstructions of the ~2cm-long skulls of some of the world's oldest dinosaur embryos in an article in Scientific Reports. The embryos, found in 1976 in Golden Gate Highlands National Park (Free State Province, South Africa) belong to South Africa's iconic dinosaur Massospondylus carinatus, a 5-meter long herbivore that nested in the Free State region 200 million years ago.

The scientific usefulness of the embryos was previously limited by their extremely fragile nature and tiny size. In 2015, scientists Kimi Chapelle and Jonah Choiniere, from the University of Witwatersrand, brought them to the European Synchrotron (ESRF) in Grenoble, France for scanning. At the ESRF, an 844 metre-ring of electrons travelling at the speed of light emits high-powered X-ray beams that can be used to non-destructively scan matter, including fossils. The embryos were scanned at an unprecedented level of detail -- at the resolution of an individual bone cell. With these data in hand, and after nearly 3 years of data processing at Wits' laboratory, the team was able to reconstruct a 3D model of the baby dinosaur skull. "No lab CT scanner in the world can generate these kinds of data," said Vincent Fernandez, one of the co-authors and scientist at the Natural History Museum in London (UK). "Only with a huge facility like the ESRF can we unlock the hidden potential of our most exciting fossils. This research is a great example of a global collaboration between Europe and the South African National Research Foundation," he adds.

Up until now, it was believed that the embryos in those eggs had died just before hatching. However, during the study, lead author Chapelle noticed similarities with the developing embryos of living dinosaur relatives (crocodiles, chickens, turtles, and lizards). By comparing which bones of the skull were present at different stages of their embryonic development, Chapelle and co-authors can now show that the Massospondylus embryos were actually much younger than previously thought and were only at 60% through their incubation period.

The team also found that each embryo had two types of teeth preserved in its developing jaws. One set was made up of very simple triangular teeth that would have been resorbed or shed before hatching, just like geckos and crocodiles today. The second set were very similar to those of adults, and would be the ones that the embryos hatched with. "I was really surprised to find that these embryos not only had teeth, but had two types of teeth. The teeth are so tiny; they range from 0.4 to 0.7mm wide. That's smaller than the tip of a toothpick!," explains Chapelle.

The conclusion of this research is that dinosaurs developed in the egg just like their reptilian relatives, whose embryonic developmental pattern hasn't changed in 200 million years. "It's incredible that in more than 250 million years of reptile evolution, the way the skull develops in the egg remains more or less the same. Goes to show -- you don't mess with a good thing!," concludes Jonah Choiniere, professor at the University of Witwatersrand and also co-author of the study.

The team hopes to apply their method to other dinosaur embryos to estimate their level of development. They will be looking at the rest of the skeleton of the Massospondylus embryos to see if it also shares similarities in development with today's dinosaur relatives. The arms and legs of the Massospondylus embryos have already been used to show that hatchlings likely walked on two legs.

How the solar system got its 'Great Divide,' and why it matters for life on Earth

Illustration of inner solar system (stock image).

Scientists, including those from the University of Colorado Boulder, have finally scaled the solar system's equivalent of the Rocky Mountain range.

In a study published today in Nature Astronomy, researchers from the United States and Japan unveil the possible origins of our cosmic neighborhood's "Great Divide." This well-known schism may have separated the solar system just after the sun first formed.

The phenomenon is a bit like how the Rocky Mountains divide North America into east and west. On the one side are "terrestrial" planet, such as Earth and Mars. They are made up of fundamentally different types of materials than the more distant "jovians," such as Jupiter and Saturn.

"The question is: How do you create this compositional dichotomy?" said lead author Ramon Brasser, a researcher at the Earth-Life Science Institute (ELSI) at the Tokyo Institute of Technology in Japan. "How do you ensure that material from the inner and outer solar system didn't mix from very early on in its history?"

Brasser and coauthor Stephen Mojzsis, a professor in CU Boulder's Department of Geological Sciences, think they have the answer, and it may just shed new light on how life originated on Earth.

A sun disk holds vital clues

The duo suggests that the early solar system was partitioned into at least two regions by a ring-like structure that formed a disk around the young sun. This disk might have held major implications for the evolution of planets and asteroids, and even the history of life on Earth.

"The most likely explanation for that compositional difference is that it emerged from an intrinsic structure of this disk of gas and dust," Mojzsis said.

Mojzsis noted that the Great Divide, a term that he and Brasser coined, does not look like much today. It is a relatively empty stretch of space that sits near Jupiter, just beyond what astronomers call the asteroid belt.

But you can still detect its presence throughout the solar system. Move sunward from that line, and most planets and asteroids tend to carry relatively low abundances of organic molecules. Go the other direction toward Jupiter and beyond, however, and a different picture emerges: Almost everything in this distant part of the solar system is made up of materials that are rich in carbon.

This dichotomy "was really a surprise when it was first found," Mojzsis said.

Many scientists assumed that Jupiter was the agent responsible for that surprise. The thinking went that the planet is so massive that it may have acted as a gravitational barrier, preventing pebbles and dust from the outer solar system from spiraling toward the sun.

But Mojzsis and Brasser were not convinced. The scientists used a series of computer simulations to explore Jupiter's role in the evolving solar system. They found that while Jupiter is big, it was probably never big enough early in its formation to entirely block the flow of rocky material from moving sunward.

"We banged our head against the wall," Brasser said. "If Jupiter wasn't the agent responsible for creating and maintaining that compositional dichotomy, what else could be?"

A solution in plain sight

For years, scientists operating an observatory in Chile called the Atacama Large Millimeter/submillimeter Array (ALMA) had noticed something unusual around distant stars: Young stellar systems were often surrounded by disks of gas and dust that, in infrared light, looked a bit like a tiger's eye.

If a similar ring existed in our own solar system billions of years ago, Brasser and Mojzsis reasoned, it could theoretically be responsible for the Great Divide.

That's because such a ring would create alternating bands of high- and low-pressure gas and dust. Those bands, in turn, might pull the solar system's earliest building blocks into several distinct sinks -- one that would have given rise to Jupiter and Saturn, and another Earth and Mars.

In the mountains, "the Great Divide causes water to drain one way or another," Mojzsis said. "It's similar to how this pressure bump would have divided material" in the solar system.

But, he added, there's a caveat: That barrier in space likely was not perfect. Some outer solar system material may still have climbed across the divide. And those fugitives could have been important for the evolution of our own world.

"Those materials that might go to the Earth would be those volatile, carbon-rich materials," Mojzsis said. "And that gives you water. It gives you organics."

The rest is Earth history.

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Materials provided by University of Colorado at Boulder. Original written by Daniel Strain. Note: Content may be edited for style and length.

Meteorite contains the oldest material on Earth: 7-billion-year-old stardust

Illustration of meteor entering Earth's atmosphere (stock image).

Stars have life cycles. They're born when bits of dust and gas floating through space find each other and collapse in on each other and heat up. They burn for millions to billions of years, and then they die. When they die, they pitch the particles that formed in their winds out into space, and those bits of stardust eventually form new stars, along with new planets and moons and meteorites. And in a meteorite that fell fifty years ago in Australia, scientists have now discovered stardust that formed 5 to 7 billion years ago -- the oldest solid material ever found on Earth.

"This is one of the most exciting studies I've worked on," says Philipp Heck, a curator at the Field Museum, associate professor at the University of Chicago, and lead author of a paper describing the findings in the Proceedings of the National Academy of Sciences. "These are the oldest solid materials ever found, and they tell us about how stars formed in our galaxy."

The materials Heck and his colleagues examined are called presolar grains-minerals formed before the Sun was born. "They're solid samples of stars, real stardust," says Heck. These bits of stardust became trapped in meteorites where they remained unchanged for billions of years, making them time capsules of the time before the solar system..

But presolar grains are hard to come by. They're rare, found only in about five percent of meteorites that have fallen to Earth, and they're tiny-a hundred of the biggest ones would fit on the period at the end of this sentence. But the Field Museum has the largest portion of the Murchison meteorite, a treasure trove of presolar grains that fell in Australia in 1969 and that the people of Murchison, Victoria, made available to science. Presolar grains for this study were isolated from the Murchison meteorite for this study about 30 years ago at the University of Chicago.

"It starts with crushing fragments of the meteorite down into a powder ," explains Jennika Greer, a graduate student at the Field Museum and the University of Chicago and co-author of the study. "Once all the pieces are segregated, it's a kind of paste, and it has a pungent characteristic-it smells like rotten peanut butter."

This "rotten-peanut-butter-meteorite paste" was then dissolved with acid, until only the presolar grains remained. "It's like burning down the haystack to find the needle," says Heck.

Once the presolar grains were isolated, the researchers figured out from what types of stars they came and how old they were. "We used exposure age data, which basically measures their exposure to cosmic rays, which are high-energy particles that fly through our galaxy and penetrate solid matter," explains Heck. "Some of these cosmic rays interact with the matter and form new elements. And the longer they get exposed, the more those elements form.

"I compare this with putting out a bucket in a rainstorm. Assuming the rainfall is constant, the amount of water that accumulates in the bucket tells you how long it was exposed," he adds. By measuring how many of these new cosmic-ray produced elements are present in a presolar grain, we can tell how long it was exposed to cosmic rays, which tells us how old it is.

The researchers learned that some of the presolar grains in their sample were the oldest ever discovered-based on how many cosmic rays they'd soaked up, most of the grains had to be 4.6 to 4.9 billion years old, and some grains were even older than 5.5 billion years. For context, our Sun is 4.6 billion years old, and Earth is 4.5 billion.

But the age of the presolar grains wasn't the end of the discovery. Since presolar grains are formed when a star dies, they can tell us about the history of stars. And 7 billion years ago, there was apparently a bumper crop of new stars forming-a sort of astral baby boom.

"We have more young grains that we expected," says Heck. "Our hypothesis is that the majority of those grains, which are 4.9 to 4.6 billion years old, formed in an episode of enhanced star formation. There was a time before the start of the Solar System when more stars formed than normal."

This finding is ammo in a debate between scientists about whether or not new stars form at a steady rate, or if there are highs and lows in the number of new stars over time. "Some people think that the star formation rate of the galaxy is constant," says Heck. "But thanks to these grains, we now have direct evidence for a period of enhanced star formation in our galaxy seven billion years ago with samples from meteorites. This is one of the key findings of our study."

Heck notes that this isn't the only unexpected thing his team found. As almost a side note to the main research questions, in examining the way that the minerals in the grains interacted with cosmic rays, the researchers also learned that presolar grains often float through space stuck together in large clusters, "like granola," says Heck. "No one thought this was possible at that scale."

Heck and his colleagues look forward to all of these discoveries furthering our knowledge of our galaxy. "With this study, we have directly determined the lifetimes of stardust. We hope this will be picked up and studied so that people can use this as input for models of the whole galactic life cycle," he says.

Heck notes that there are lifetimes' worth of questions left to answer about presolar grains and the early Solar System. "I wish we had more people working on it to learn more about our home galaxy, the Milky Way," he says.

"Once learning about this, how do you want to study anything else?" says Greer. "It's awesome, it's the most interesting thing in the world."

"I always wanted to do astronomy with geological samples I can hold in my hand," says Heck. "It's so exciting to look at the history of our galaxy. Stardust is the oldest material to reach Earth, and from it, we can learn about our parent stars, the origin of the carbon in our bodies, the origin of the oxygen we breathe. With stardust, we can trace that material back to the time before the Sun."

"It's the next best thing to being able to take a sample directly from a star," says Greer.

This study was contributed to by researchers from the Field Museum, University of Chicago, Lawrence Livermore National Laboratory, Washington University, Harvard Medical School, ETH Zurich, and the Australian National University. Funding was provided by NASA, the TAWANI Foundation, the National Science Foundation, the Department of Energy, the Swiss National Science Foundation, the Brazilian National Council for Scientific and Technological Development and the Field Museum's Science and Scholarship Funding Committee.

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Materials provided by Field Museum. Note: Content may be edited for style and length.

How many breaths we have.

On average, a person at rest takes 

about 16 breaths per minute. This 

means we breathe about 960 breaths 

an hour, 23,040 breaths a day, 8,409,600 

a year. Unless we get a lot of exercise. 

The person who lives to 80 will take about 

672,768,000 breaths in a lifetime.

NASA's treasure map for water ice on Mars

Mars illustration (stock image).

NASA has big plans for returning astronauts to the Moon in 2024, a stepping stone on the path to sending humans to Mars. But where should the first people on the Red Planet land?

A new paper published in Geophysical Research Letters will help by providing a map of water ice believed to be as little as an inch (2.5 centimeters) below the surface.

Water ice will be a key consideration for any potential landing site. With little room to spare aboard a spacecraft, any human missions to Mars will have to harvest what's already available for drinking water and making rocket fuel.

NASA calls this concept "in situ resource utilization," and it's an important factor in selecting human landing sites on Mars. Satellites orbiting Mars are essential in helping scientists determine the best places for building the first Martian research station. The authors of the new paper make use of data from two of those spacecraft, NASA's Mars Reconnaissance Orbiter (MRO) and Mars Odyssey orbiter, to locate water ice that could potentially be within reach of astronauts on the Red Planet.

"You wouldn't need a backhoe to dig up this ice. You could use a shovel," said the paper's lead author, Sylvain Piqueux of NASA's Jet Propulsion Laboratory in Pasadena, California. "We're continuing to collect data on buried ice on Mars, zeroing in on the best places for astronauts to land."

Buried Treasure on Mars

Liquid water can't last in the thin air of Mars; with so little air pressure, it evaporates from a solid to a gas when exposed to the atmosphere.

Martian water ice is locked away underground throughout the planet's mid-latitudes. These regions near the poles have been studied by NASA's Phoenix lander, which scraped up ice, and MRO, which has taken many images from space of meteor impacts that have excavated this ice. To find ice that astronauts could easily dig up, the study's authors relied on two heat-sensitive instruments: MRO's Mars Climate Sounder and the Thermal Emission Imaging System (THEMIS) camera on Mars Odyssey.

Why use heat-sensitive instruments when looking for ice? Buried water ice changes the temperature of the Martian surface. The study's authors cross-referenced temperatures suggestive of ice with other data, such as reservoirs of ice detected by radar or seen after meteor impacts. Data from Odyssey's Gamma Ray Spectrometer, which is tailor-made for mapping water ice deposits, were also useful.

As expected, all these data suggest a trove of water ice throughout the Martian poles and mid-latitudes. But the map reveals particularly shallow deposits that future mission planners may want to study further.

Picking a Landing Site

While there are lots of places on Mars scientists would like to visit, few would make practical landing sites for astronauts. Most scientists have homed in on the northern and southern mid-latitudes, which have more plentiful sunlight and warmer temperatures than the poles. But there's a heavy preference for landing in the northern hemisphere, which is generally lower in elevation and provides more atmosphere to slow a landing spacecraft.

A large portion of a region called Arcadia Planitia is the most tempting target in the northern hemisphere. The map shows lots of blue and purple in this region, representing water ice less than one foot (30 centimeters) below the surface; warm colors are over two feet (60 centimeters) deep. Sprawling black zones on the map represent areas where a landing spacecraft would sink into fine dust.

What's Next?

Piqueux is planning a comprehensive campaign to continue studying buried ice across different seasons, watching how the abundance of this resource changes over time.

The more we look for near-surface ice, the more we find," said MRO Deputy Project Scientist Leslie Tamppari of JPL. "Observing Mars with multiple spacecraft over the course of years continues to provide us with new ways of discovering this ice."

JPL manages the MRO and Mars Odyssey missions for NASA's Science Mission Directorate in Washington. Lockheed Martin Space in Denver built both orbiters. JPL built and operates the Mars Climate Sounder instrument. THEMIS was built and is operated by Arizona State University in Tempe. The Gamma Ray Spectrometer was built and is operated by the University of Arizona in Tucson.

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Materials provided by NASA/Jet Propulsion Laboratory. Note: Content may be edited for style and length.

Researchers build a particle accelerator that fits on a chip

Subatomic particle collisions illustration (stock image).

On a hillside above Stanford University, the SLAC National Accelerator Laboratory operates a scientific instrument nearly 2 miles long. In this giant accelerator, a stream of electrons flows through a vacuum pipe, as bursts of microwave radiation nudge the particles ever-faster forward until their velocity approaches the speed of light, creating a powerful beam that scientists from around the world use to probe the atomic and molecular structures of inorganic and biological materials.

Now, for the first time, scientists at Stanford and SLAC have created a silicon chip that can accelerate electrons -- albeit at a fraction of the velocity of that massive instrument -- using an infrared laser to deliver, in less than a hair's width, the sort of energy boost that takes microwaves many feet.

Writing in the Jan. 3 issue of Science, a team led by electrical engineer Jelena Vuckovic explained how they carved a nanoscale channel out of silicon, sealed it in a vacuum and sent electrons through this cavity while pulses of infrared light -- to which silicon is as transparent as glass is to visible light -- were transmitted by the channel walls to speed the electrons along.

The accelerator-on-a-chip demonstrated in Science is just a prototype, but Vuckovic said its design and fabrication techniques can be scaled up to deliver particle beams accelerated enough to perform cutting-edge experiments in chemistry, materials science and biological discovery that don't require the power of a massive accelerator.

"The largest accelerators are like powerful telescopes. There are only a few in the world and scientists must come to places like SLAC to use them," Vuckovic said. "We want to miniaturize accelerator technology in a way that makes it a more accessible research tool."

Team members liken their approach to the way that computing evolved from the mainframe to the smaller but still useful PC. Accelerator-on-a-chip technology could also lead to new cancer radiation therapies, said physicist Robert Byer, a co-author of the Science paper. Again, it's a matter of size. Today, medical X-ray machines fill a room and deliver a beam of radiation that's tough to focus on tumors, requiring patients to wear lead shields to minimize collateral damage.

"In this paper we begin to show how it might be possible to deliver electron beam radiation directly to a tumor, leaving healthy tissue unaffected," said Byer, who leads the Accelerator on a Chip International Program, or ACHIP, a broader effort of which this current research is a part.

Inverse design

In their paper, Vuckovic and graduate student Neil Sapra, the first author, explain how the team built a chip that fires pulses of infrared light through silicon to hit electrons at just the right moment, and just the right angle, to move them forward just a bit faster than before.

To accomplish this, they turned the design process upside down. In a traditional accelerator, like the one at SLAC, engineers generally draft a basic design, then run simulations to physically arrange the microwave bursts to deliver the greatest possible acceleration. But microwaves measure 4 inches from peak to trough, while infrared light has a wavelength one-tenth the width of a human hair. That difference explains why infrared light can accelerate electrons in such short distances compared to microwaves. But this also means that the chip's physical features must be 100,000 times smaller than the copper structures in a traditional accelerator. This demands a new approach to engineering based on silicon integrated photonics and lithography.

Vuckovic's team solved the problem using inverse design algorithms that her lab has developed. These algorithms allowed the researchers to work backward, by specifying how much light energy they wanted the chip to deliver, and tasking the software with suggesting how to build the right nanoscale structures required to bring the photons into proper contact with the flow of electrons.

"Sometimes, inverse designs can produce solutions that a human engineer might not have thought of," said R. Joel England, a SLAC staff scientist and co-author on the Science paper.

The design algorithm came up with a chip layout that seems almost otherworldly. Imagine nanoscale mesas, separated by a channel, etched out of silicon. Electrons flowing through the channel run a gantlet of silicon wires, poking through the canyon wall at strategic locations. Each time the laser pulses -- which it does 100,000 times a second -- a burst of photons hits a bunch of electrons, accelerating them forward. All of this occurs in less than a hair's width, on the surface of a vacuum-sealed silicon chip, made by team members at Stanford.

The researchers want to accelerate electrons to 94 percent of the speed of light, or 1 million electron volts (1MeV), to create a particle flow powerful enough for research or medical purposes. This prototype chip provides only a single stage of acceleration, and the electron flow would have to pass through around 1,000 of these stages to achieve 1MeV. But that's not as daunting at it may seem, said Vuckovic, because this prototype accelerator-on-a-chip is a fully integrated circuit. That means all of the critical functions needed to create acceleration are built right into the chip, and increasing its capabilities should be reasonably straightforward.

The researchers plan to pack a thousand stages of acceleration into roughly an inch of chip space by the end of 2020 to reach their 1MeV target. Although that would be an important milestone, such a device would still pale in power alongside the capabilities of the SLAC research accelerator, which can generate energy levels 30,000 times greater than 1MeV. But Byer believes that, just as transistors eventually replaced vacuum tubes in electronics, light-based devices will one day challenge the capabilities of microwave-driven accelerators.

Meanwhile, in anticipation of developing a 1MeV accelerator on a chip, electrical engineer Olav Solgaard, a co-author on the paper, has already begun work on a possible cancer-fighting application. Today, highly energized electrons aren't used for radiation therapy because they would burn the skin. Solgaard is working on a way to channel high-energy electrons from a chip-sized accelerator through a catheter-like vacuum tube that could be inserted below the skin, right alongside a tumor, using the particle beam to administer radiation therapy surgically.

"We can derive medical benefits from the miniaturization of accelerator technology in addition to the research applications," Solgaard said.

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Story Source:

Materials provided by Stanford University. Original written by Tom Abate. Note: Content may be edited for style and length.

Forgetfulness might depend on time of day

Pocket watch (stock image).

Can't remember something? Try waiting until later in the day. Researchers identified a gene in mice that seems to influence memory recall at different times of day and tracked how it causes mice to be more forgetful just before they normally wake up.

"We may have identified the first gene in mice specific to memory retrieval," said Professor Satoshi Kida from the University of Tokyo Department of Applied Biological Chemistry.

Every time you forget something, it could be because you didn't truly learn it -- like the name of the person you were just introduced to a minute ago; or it could be because you are not able to recall the information from where it is stored in your brain -- like the lyrics of your favorite song slipping your mind.

Many memory researchers study how new memories are made. The biology of forgetting is more complicated to study because of the difficulties of distinguishing between not knowing and not recalling.

"We designed a memory test that can differentiate between not learning versus knowing but not being able to remember," said Kida.

Researchers tested the memories of young adult male and female mice. In the "learning," or training, phase of the memory tests, researchers allowed mice to explore a new object for a few minutes.

Later, in the "recall" phase of the test, researchers observed how long the mice touched the object when it was reintroduced. Mice spend less time touching objects that they remember seeing previously. Researchers tested the mice's recall by reintroducing the same object at different times of day.

They did the same experiments with healthy mice and mice without BMAL1, a protein that regulates the expression of many other genes. BMAL1 normally fluctuates between low levels just before waking up and high levels before going to sleep.

Mice trained just before they normally woke up and tested just after they normally went to sleep did recognize the object.

Mice trained at the same time -- just before they normally woke up -- but tested 24 hours later did not recognize the object.

Healthy mice and mice without BMAL1 had the same pattern of results, but the mice without BMAL1 were even more forgetful just before they normally woke up. Researchers saw the same results when they tested mice on recognizing an object or recognizing another mouse.

Something about the time of day just before they normally wake up, when BMAL1 levels are normally low, causes mice to not recall something they definitely learned and know.

According to Kida, the memory research community has previously suspected that the body's internal, or circadian, clock that is responsible for regulating sleep-wake cycles also affects learning and memory formation.

"Now we have evidence that the circadian clocks are regulating memory recall," said Kida.

Researchers have traced the role of BMAL1 in memory retrieval to a specific area of the brain called the hippocampus. Additionally, researchers connected normal BMAL1 to activation of dopamine receptors and modification of other small signaling molecules in the brain.

"If we can identify ways to boost memory retrieval through this BMAL1 pathway, then we can think about applications to human diseases of memory deficit, like dementia and Alzheimer's disease," said Kida.

However, the purpose of having memory recall abilities that naturally fluctuate depending on the time of day remains a mystery.

"We really want to know what is the evolutionary benefit of having naturally impaired memory recall at certain times of day," said Kida.

About the research

Mice are naturally nocturnal. When measured in units of time using zeitgeber, the environmental cue of light turning on, mice are usually asleep from Zeitgeber Time 1 to 12 and awake from Zeitgeber Time 12 to 24. The term "just before normally waking up" refers to Zeitgeber Time 10, while the term "just after normally going to sleep" refers to Zeitgeber Time 4.

Collaborators at the Tokyo University of Agriculture and the University of Toronto also contributed to this research.

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Story Source:

Materials provided by University of Tokyo. Note: Content may be edited for style and length.

The Science of Sleep: A Brief Guide on How to Sleep Better Every Night

If you want to learn how to sleep better, then you're in the right place. This guide will walk you through everything you need to know if you want to get better sleep. I'll explain the science of sleep and how it works, discuss why many people suffer from sleep deprivation without knowing it, and offer practical tips for getting better sleep and having more energy.

Plain and simple, the purpose of this guide is to explain the science of how to sleep better. You can click the links below to jump to a particular section or simply scroll down to read everything. At the end of this page, you’ll find a complete list of all the articles I have written on sleep.

I. The Science of Sleep

Sleep is one of the strangest things we do each day. The average adult will spend 36 percent of his or her life asleep. For one-third of our time on earth, we transition from the vibrant, thoughtful, active organisms we are during the day and power down into a quiet state of hibernation.

But what is sleep, exactly? Why is it so important and so restorative for our bodies and minds? How does it impact our lives when we are awake?

The Purpose of Sleep

Sleep serves multiple purposes that are essential to your brain and body. Let's break down some of the most important ones.

The first purpose of sleep is restoration. Every day, your brain accumulates metabolic waste as it goes about its normal neural activities. While this is completely normal, too much accumulation of these waste products has been linked to neurological disorders such as Alzheimer's disease.

Alright, so how do we get rid of metabolic waste? Recent research has suggested that sleep plays a crucial role in cleaning out the brain each night. While these toxins can be flushed out during waking hours, researchers have found that clearance during sleep is as much as two-fold faster than during waking hours.

The way this process occurs is fairly remarkable:

During sleep, brain cells actually shrink by 60 percent, allowing the brain's waste-removal system—called the glymphatic system—to essentially “take out the trash” more easily. The result? Your brain is restored during sleep, and you wake up refreshed and with a clear mind.

The second purpose of sleep is memory consolidation. Sleep is crucial for memory consolidation, which is the process that maintains and strengthens your long-term memories. Insufficient or fragmented sleep can hamper your ability to form both concrete memories (facts and figures) and emotional memories.

Finally, sleep is paramount for metabolic health. Studies have shown that when you sleep 5.5 hours per night instead of 8.5 hours per night, a lower proportion of the energy you burn comes from fat, while more comes from carbohydrate and protein. This can predispose you to fat gain and muscle loss. Additionally, insufficient sleep or abnormal sleep cycles can lead to insulin insensitivity and metabolic syndrome, increasing your risk of diabetes and heart disease.

Motivation: The Scientific Guide on How to Get and Stay Motivated

Motivation is a powerful, yet tricky beast. Sometimes it is really easy to get motivated, and you find yourself wrapped up in a whirlwind of excitement. Other times, it is nearly impossible to figure out how to motivate yourself and you're trapped in a death spiral of procrastination. This page contains the best ideas and most useful research on how to get and stay motivated.

This isn't going to be some rah-rah, pumped-up motivational speech. (That's not my style.) Instead, we're going to break down the science behind how to get motivated in the first place and how to stay motivated for the long-run. Whether you're trying to figure out how to motivate yourself or how to motivate a team, this page should cover everything you need to know.

You can click the links below to jump to a particular section or simply scroll down to read everything. At the end of this page, you'll find a complete list of all the articles I have written on motivation.

What is Motivation?

So what is motivation, exactly? The author Steven Pressfield has a great line in his book, The War of Art, which I think gets at the core of motivation. To paraphrase Pressfield, “At some point, the pain of not doing it becomes greater than the pain of doing it.”

Common Misconceptions About Motivation

One of the most surprising things about motivation is that it often comes after starting a new behavior, not before. We have this common misconception that motivation arrives as a result of passively consuming a motivational video or reading an inspirational book. However, active inspiration can be a far more powerful motivator.

Common Misconceptions About Motivation

One of the most surprising things about motivation is that it often comes after starting a new behavior, not before. We have this common misconception that motivation arrives as a result of passively consuming a motivational video or reading an inspirational book. However, active inspiration can be a far more powerful motivator.

The work of top creatives isn’t dependent upon motivation or inspiration, but rather it follows a consistent pattern and routine. Here are some examples of how you can apply ritual and routine to get motivated:

• Exercise more consistently: Use the same warm up routine in the gym.
• Become more creative: Follow a creative ritual before you start writing or painting or singing.
• Start each day stress-free: Create a five-minute morning meditation ritual.
• Sleep better: Follow a “power down” routine before bed.